Search on: RIBOSOME INACTIVATING PROTEINS 
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Descriptor English:   Ribosome Inactivating Proteins 
Descriptor Spanish:   Proteínas Inactivantes de Ribosomas 
Descriptor Portuguese:   Proteínas Inativadoras de Ribossomos 
Synonyms English:   RNA N-Glycosidase  
Tree Number:   D08.811.277.450.430.700
D12.776.765.710
Definition English:   N-Glycosidases that remove adenines from RIBOSOMAL RNA, depurinating the conserved alpha-sarcin loop of 28S RIBOSOMAL RNA. They often consist of a toxic A subunit and a binding lectin B subunit. They may be considered as PROTEIN SYNTHESIS INHIBITORS. They are found in many PLANTS and have cytotoxic and antiviral activity. 
Pharmacological Action:   Protein Synthesis Inhibitors
 
History Note English:   2008(1988) 
Allowable Qualifiers English:  
administration & dosage adverse effects
antagonists & inhibitors analysis
biosynthesis blood
cerebrospinal fluid chemistry
classification chemical synthesis
contraindications drug effects
deficiency diagnostic use
economics genetics
history immunology
isolation & purification metabolism
pharmacology physiology
pharmacokinetics poisoning
radiation effects supply & distribution
secretion standards
toxicity therapeutic use
ultrastructure urine
Record Number:   52713 
Unique Identifier:   D054788 

Occurrence in VHL:
 

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